rs121918464
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the effects of gain-of-function (GOF) E76K-mutant Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) on the biological behaviors of glioblastoma (GBM) cells, and explore the molecular mechanisms of GBM progression.
|
31807022 |
2019 |
rs1249080185
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the effects of gain-of-function (GOF) E76K-mutant Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) on the biological behaviors of glioblastoma (GBM) cells, and explore the molecular mechanisms of GBM progression.
|
31807022 |
2019 |
rs562015640
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the effects of gain-of-function (GOF) E76K-mutant Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) on the biological behaviors of glioblastoma (GBM) cells, and explore the molecular mechanisms of GBM progression.
|
31807022 |
2019 |
rs121913500
|
|
|
0.100 |
GeneticVariation |
BEFREE |
For this reason, it was suggested that immunohistochemistry against IDH1 R132H is sufficient to classify GBM as IDH wild-type in this age group.
|
31758617 |
2020 |
rs118101777
|
|
|
0.080 |
GeneticVariation |
BEFREE |
For this reason, it was suggested that immunohistochemistry against IDH1 R132H is sufficient to classify GBM as IDH wild-type in this age group.
|
31758617 |
2020 |
rs121913500
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Tumor-to-muscle ratios were also significantly higher in U251/IDH1 R132H tumo</span>rs (3.36 ± </span>0.41 vs. 1.88 ± 0.59, p = 0.0030).
|
31667733 |
2019 |
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, in patients with GBM receiving RCT with TMZ, no correlation with survival was found for the SNV:s 1236C>T, 2677G>T/A, and 3435C>T of ABCB1.
|
31624332 |
2020 |
rs1128503
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, in patients with GBM receiving RCT with TMZ, no correlation with survival was found for the SNV:s 1236C>T, 2677G>T/A, and 3435C>T of ABCB1.
|
31624332 |
2020 |
rs144551722
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs144551722 SNP was a significant predictor of development of glioblastoma in males (p-value = 0.0056) but not in females even after correction for multiple testing.
|
31556016 |
2019 |
rs12885300
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs of DIO1 gene (rs2235544) and DIO2 gene (rs12885300) have independent prognostic significance in glioblastoma patients.
|
31452060 |
2019 |
rs2235544
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs of DIO1 gene (rs2235544) and DIO2 gene (rs12885300) have independent prognostic significance in glioblastoma patients.
|
31452060 |
2019 |
rs113488022
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Epithelioid GBM with BRAF V600E mutation can be considered a good treatment indication for precision medicine, and this patient-derived cell line should be useful for prediction of the tumor response and clarification of its biological characteristics.
|
31345255 |
2019 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Epithelioid GBM with BRAF V600E mutation can be considered a good treatment indication for precision medicine, and this patient-derived cell line should be useful for prediction of the tumor response and clarification of its biological characteristics.
|
31345255 |
2019 |
rs28357681
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Integrated Approach Reveals Role of Mitochondrial Germ-Line Mutation F18L in Respiratory Chain, Oxidative Alterations, Drug Sensitivity, and Patient Prognosis in Glioblastoma.
|
31323957 |
2019 |
rs113488022
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Epithelioid glioblastoma is a recognized glioblastoma variant, recently added to the World Health Organization brain tumor classification, with similar prognosis as the classic variant and B-Raf V600E mutations in 50% of the cases.
|
31258848 |
2019 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Epithelioid glioblastoma is a recognized glioblastoma variant, recently added to the World Health Organization brain tumor classification, with similar prognosis as the classic variant and B-Raf V600E mutations in 50% of the cases.
|
31258848 |
2019 |
rs1800470
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It seems that polymorphism of T29C (L10P, rs1982073, or rs1800470), which has been studied in various cancers such as breast and colon, creates the significant differences plays an important role in GBM prognosis and treatment.
|
31160907 |
2019 |
rs1982073
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Evaluation of rs1982073 polymorphism of transforming growth factor-β1 in glioblastoma.
|
31160907 |
2019 |
rs121913500
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The R132H mutation in isocitrate dehydrogenase 1 (IDH1<sup>R132H</sup>) is commonly observed and associated with better survival in glioblastoma multiforme (GBM), a malignant brain tumor.
|
31151327 |
2019 |
rs1161136341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The R132H mutation in isocitrate dehydrogenase 1 (IDH1<sup>R132H</sup>) is commonly observed and associated with better survival in glioblastoma multiforme (GBM), a malignant brain tumor.
|
31151327 |
2019 |
rs774238794
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The R132H mutation in isocitrate dehydrogenase 1 (IDH1<sup>R132H</sup>) is commonly observed and associated with better survival in glioblastoma multiforme (GBM), a malignant brain tumor.
|
31151327 |
2019 |
rs2440472
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between autocrine motility factor receptor gene polymorphism (rs2440472, rs373191257) and glioblastoma multiform in a representative Iranian population.
|
30595704 |
2018 |
rs373191257
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between autocrine motility factor receptor gene polymorphism (rs2440472, rs373191257) and glioblastoma multiform in a representative Iranian population.
|
30595704 |
2018 |
rs149840192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Studies have shown p.A289V mutation responding to tyrosine kinase inhibitors (TKIs) in glioblastoma cell lines suggesting the point mutation as a potential therapeutic target.
|
30572543 |
2018 |
rs4644
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation.
|
30341098 |
2019 |